Guignard Lab
We develop computational methods to quantify morphogenesis at the single-cell scale in whole organisms throughout their development. Our research sits at the intersection of computer vision, machine learning, and developmental biology.
Highlights
Our Research
How do embryos reproducibly build complex organisms from a single cell? We develop algorithms and pipelines — combining graph methods, machine learning, and big data — to analyze fluorescence microscopy and spatial transcriptomics data at single-cell resolution.
Our Software
We build open-source tools for 3D image registration, spatial transcriptomics analysis, organoid quantification, and lineage tree handling — designed to be reusable by the broader community.
Our Team
We are a diverse team of computer scientists, physicists, biologists, and mathematicians based at IBDM & the Turing Centre for Living Systems, Aix-Marseille Université & CNRS, Marseille.