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Guignard Lab

At the interface between Computer Science and Developmental Biology


Our Research

Drosophila reconstruction

Building average representations of embryogenesis.

Embryos develop following a predefined set of rules, in a reproducible manner, to allow the organization of a functioning organism.

In our group, we are interested in developing computational methods to quantitatively characterise and understand the origins of this developmental reproducibility during embryogenesis.

We are pursuing two main research axes:

  • Building average representatives of a population of developing embryos

  • Characterising developmental variability across spatio-temporal scales

For these two research axes, we look at 3D+time morphological dataset acquired using light microscopy. We also look at spatial transcriptomics dataset acquired, for example, using SlideSeqv2 for example.

Phallusia mammillata embryo


Videos of developing embryos (usually)

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